Emergency services remained at the scene of the major incident at Bosley Wood Treatment thoughout the weekend.
Efforts continue to try and locate the whereabouts of four people unaccounted for since the incident happened on Friday morning.
The names of the four people who remain unaccounted were confirmed as Derek Moore, William Barks, Jason Shingler and Dorothy Bailey.
Four people who remain unaccounted: (clockwise) Derek Moore, William Barks, Jason Shingler and Dorothy Bailey,
The operation at the site continued on two areas identified by the search and rescue efforts.
Fire chiefs said temperatures at the scene topped 1,000 degrees celsius in the aftermath of the blast, which caused a four-storey building to collapse.
A Cheshire Police spokesman said: “This is a particularly difficult time for the families involved and it is with regret that Cheshire Police are confirming that a body has been located in one of the two areas being searched.”
“The body has not been positively identified.”
“The four families who are awaiting news about their family member have been informed of this development and HM Coroner has been informed.”
“The thoughts of all the agencies involved are with the families at this time and Cheshire Police are asking members of the media to respect the family’s privacy as they try to come to terms with this latest development.”
The Boden Group, the Wigan company which owns the mill, which used to employ 50 people, has yet to comment on the incident.
Details have emerged that council enforcement officers were on the site two weeks ago to make sure the firm cleared the area after complaints of saw dust. The site was also struck by fires in 2010 and 2012.
Michael Jones, leader of Cheshire East council, said: “We were on site two weeks ago clearing it up and they did well to clear it up. We will produce that evidence as and when necessary.
“The fact is this is the sort of industry that has a lot of problems tied to the dust and what happens around it.”
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